Endo-Solution 17% EDTA (200ml)

ENDO-SOLUTION · 17% EDTA · 200 ML

Smear layer removalChelationCanal preparationDentist use only

The chelation step, in a single bottle

The smear layer that instrumentation leaves behind is inorganic, and hypochlorite does not lift it. Cerkamed describe Endo-Solution as flushing out calcium and magnesium ions to soften the dentine surface layer so it can be removed, exposing the dentine tubule orifices. It is the middle step of the sequence the ESE guideline uses as its reference.

This pack: Endo-Solution 17% EDTA (200ml)

What it is for

›  Cerkamed: "by flushing out calcium and magnesium ions, disodium edetate (EDTA) softens dentine surface layer to allow its easier removal and canal unblocking".

›  Removes the smear layer and exposes the dentine tubule orifices.

›  Applied with a blunt-ended, lateral-bore needle, working the canal mechanically for about a minute.

›  Cerkamed are explicit: "do not leave product in the canal or the tooth cavity between visits", as it may lead to oversoftening of dentine.

›  Cerkamed mark the product "TO BE USED BY DENTIST ONLY".

Irrigation, as the ESE guideline sets it out

The European Society of Endodontology's S3-level guideline takes sodium hypochlorite followed by EDTA as its reference sequence – it is the comparator every other irrigant regimen in the review was measured against. For asymptomatic apical periodontitis in permanent teeth it states that NaOCl (1%–5.25%) followed by EDTA, then NaOCl again, may be considered (open-grade recommendation). Concentration is the clinician's choice: the guideline found insufficient evidence to prefer one over another, and we stock both ends of the range it names.

Rinse with purified water between steps. Cerkamed direct that the two are not run straight into one another – "the EDTA contained in the product neutralises the effect of NaOCl" – and that "purified water should be used to rinse root canals between the use of fluids". The same applies to citric acid, and to chlorhexidine, which forms a precipitate with either.

Why not standard thin bleach?

Because you cannot be sure what is going into the canal. A 2026 randomised trial compared a domestic bleach with a medical-grade sodium hypochlorite, both diluted to what the operators took to be 2.5%. Measured afterwards, the domestic product was 6.13% sodium hypochlorite against the medical-grade at 4.83% – and patients in the domestic group reported significantly more pain at six and twelve hours, which the authors put down to the higher chlorine content together with the surfactants household bleach carries. (Nasr & Hassan, BMC Oral Health 2026; randomised controlled trial, 60 patients, one product on each side.)

A medical device carries a stated concentration, a batch number, an expiry date and a safety data sheet, and it is manufactured for this purpose. A household bleach is formulated to clean a surface to a price; its strength is not controlled for use in a root canal, and it is not intended for one.

This covers the irrigation step only. The same guideline also addresses diagnosis, instrumentation, intracanal dressing and adjunctive disinfection. › Read the full ESE guideline – Duncan HF et al., International Endodontic Journal 2023 (open access).

What does it actually do?

Cerkamed describe it as flushing out calcium and magnesium ions, "softening the dentine surface layer to allow its easier removal and canal unblocking", which removes the smear layer left by instrumentation and exposes the tubule orifices.

Can I leave it in between appointments?

Cerkamed are explicit: "do not leave product in the canal or the tooth cavity between visits", as it may lead to oversoftening of dentine.

Can it follow hypochlorite directly?

No. Cerkamed state that the EDTA "neutralises the effect of NaOCl", and that "purified water should be used to rinse root canals between the use of fluids".

Complete the sequence

Cerkamed · Cerkamed Endo-Solution 17% EDTA 200ml · REF CER-W-ES200